Researchers have shown that transplanting stem cells derived from normal mouse blood vessels into the hearts of mice that model the pathology associated with Duchenne muscular dystrophy (DMD) prevents the decrease in heart function associated with DMD.
In the new study, researchers injected stem cells known as
aorta-derived mesoangioblasts (ADM) into the hearts of
dystrophin-deficient mice that serve as a model for human DMD. The ADM
stem cells have a working copy of the dystrophin gene.
This stem cell therapy prevented or delayed heart problems in mice that did not already show signs of the functional or structural defects typical of Duchenne muscular dystrophy.
Adapted from the University of Illinois announcement story. Read further here.